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Antimicrobial peptide mimetic minimalistic approach leads to very short peptide amphiphiles-gold nanostructures for potent antibacterial activity
ChemMedChem ( IF 3.4 ) Pub Date : 2024-02-01 , DOI: 10.1002/cmdc.202300576
Narayan Swain 1 , Shruti Sharma 1 , Rahul Maitra 2 , Deepnashi Saxena 2 , Aanand Kautu 3 , Ramesh Singh 4 , Khushboo Kesharwani 4 , Sidharth Chopra 2 , Khashti Ballabh Joshi 5
Affiliation  

Owing to tryptophan amino acid‘s unique photophysical properties, strong membrane-disrupting activity and low cytotoxicity, directed a straightforward lipidated version followed by facile synthesis of gold nanoparticles. These hybrid nanomaterials were proposed as potential antibacterial agents.

中文翻译:

抗菌肽模拟简约方法产生非常短的肽两亲物-金纳米结构,具有有效的抗菌活性

由于色氨酸氨基酸独特的光物理性质、强膜破坏活性和低细胞毒性,直接直接脂质化,然后轻松合成金纳米粒子。这些杂化纳米材料被提议作为潜在的抗菌剂。
更新日期:2024-02-01
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