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Giving Breath to Motor Neurons: Noninvasive Mechanical Ventilation Slows Disease Progression in Amyotrophic Lateral Sclerosis
Annals of Neurology ( IF 11.2 ) Pub Date : 2024-01-29 , DOI: 10.1002/ana.26875
Maurizio Grassano 1 , Emanuele Koumantakis 2, 3 , Umberto Manera 1, 4 , Antonio Canosa 1, 4 , Rosario Vasta 1 , Francesca Palumbo 1 , Giuseppe Fuda 1 , Paolina Salamone 1 , Giulia Marchese 1 , Federico Casale 1 , Lorena Charrier 2 , Gabriele Mora 1 , Cristina Moglia 1, 4 , Andrea Calvo 1, 4 , Adriano Chiò 1, 4, 5
Affiliation  

Noninvasive mechanical ventilation (NIMV) improves amyotrophic lateral sclerosis (ALS) quality of life and survival. However, data about its effect on disease progression are still lacking. Here, we test whether NIMV use changed the rate of functional decline among ALS patients.

中文翻译:

为运动神经元提供呼吸:无创机械通气可减缓肌萎缩侧索硬化症的疾病进展

无创机械通气 (NIMV) 可改善肌萎缩侧索硬化症 (ALS) 的生活质量和生存率。然而,仍然缺乏关于其对疾病进展影响的数据。在这里,我们测试 NIMV 的使用是否改变了 ALS 患者的功能衰退率。
更新日期:2024-01-29
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