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Cerebellar projections to the substantia nigra modulate basal ganglia dopamine levels
Nature Neuroscience ( IF 25.0 ) Pub Date : 2024-01-31 , DOI: 10.1038/s41593-024-01587-6


A widespread group of cerebellar projections form monosynaptic excitatory synapses with neurons throughout the substantia nigra pars compacta (SNc). These projections contain information associated with movement and reward and can rapidly increase SNc neuron activity, and thereby basal ganglia dopamine levels, which contribute to movement initiation, vigor and reward processing.

中文翻译:

小脑对黑质的投射调节基底神经节多巴胺水平

一组广泛的小脑投射与整个黑质致密部 (SNc) 的神经元形成单突触兴奋性突触。这些预测包含与运动和奖励相关的信息,可以快速增加 SNc 神经元的活动,从而提高基底神经节多巴胺水平,这有助于运动启动、活力和奖励处理。
更新日期:2024-01-31
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