The recognition of noise exposure as a prominent environmental determinant of public health has grown substantially. While recent years have yielded a wealth of evidence linking environmental noise exposure primarily to cardiovascular ailments, our understanding of the detrimental effects of noise on the brain and mental health outcomes remains limited. Despite being a nascent research area, an increasing body of compelling research and conclusive findings confirms that exposure to noise, particularly from sources such as traffic, can potentially impact the central nervous system. These harms of noise increase the susceptibility to mental health conditions such as depression, anxiety, suicide, and behavioral problems in children and adolescents. From a mechanistic perspective, several investigations propose direct adverse phenotypic changes in brain tissue by noise (e.g. neuroinflammation, cerebral oxidative stress), in addition to feedback signaling by remote organ damage, dysregulated immune cells, and impaired circadian rhythms, which may collectively contribute to noise-dependent impairment of mental health. This concise review linking noise exposure to mental health outcomes seeks to fill research gaps by assessing current findings from studies involving both humans and animals.

人们越来越认识到噪声暴露是公共卫生的一个重要环境决定因素。尽管近年来已有大量证据表明环境噪声暴露主要与心血管疾病有关，但我们对噪声对大脑和心理健康结果的有害影响的了解仍然有限。尽管这是一个新兴的研究领域，但越来越多的令人信服的研究和结论性发现证实，暴露于噪音，特别是来自交通等来源的噪音，可能会影响中枢神经系统。噪音的这些危害会增加儿童和青少年患抑郁、焦虑、自杀和行为问题等心理健康问题的可能性。从机制的角度来看，一些研究提出，除了远程器官损伤、免疫细胞失调和昼夜节律受损的反馈信号之外，噪声（例如神经炎症、脑氧化应激）也会对脑组织产生直接不利的表型变化，这些可能共同导致噪音依赖性心理健康损害。这篇简明的综述将噪音暴露与心理健康结果联系起来，旨在通过评估涉及人类和动物的研究的当前结果来填补研究空白​​。