An analysis based on datasets from four studies of memory and ageing reveals differences in the relationship of cognition with cerebrospinal fluid, but not imaging, biomarkers for Alzheimer disease between self-identified Black and White participants. These findings highlight the importance of precision medicine to address Alzheimer disease disparities across diverse populations. A study now reveals that CSF, but not imaging, biomarkers for Alzheimer disease show weaker correlation to cognitive measures in Black people than in White people. The findings offer insights into Alzheimer disease biomarker utility across racially diverse groups.

中文翻译：

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应对阿尔茨海默病生物标志物中种族差异的复杂性

基于四项记忆和衰老研究数据集的分析揭示了自我认同的黑人和白人参与者之间认知与脑脊液关系的差异，但与成像（阿尔茨海默病生物标志物）的关系无关。这些发现凸显了精准医学对于解决不同人群阿尔茨海默病差异的重要性。现在的一项研究表明，与白人相比，阿尔茨海默病的脑脊液生物标志物（而非成像生物标志物）与黑人认知测量的相关性较白人弱。这些发现提供了关于阿尔茨海默病生物标志物在不同种族群体中的效用的见解。