To limit the catastrophic effects of the increasing bacterial resistance to antimicrobials on health, food, environmental, and geopolitical security, and ensure that no country or region is left behind, a coordinated global approach is required. In this Viewpoint, we argue that the diverging resource availabilities, needs, and priorities of the Global North and the Global South in terms of the actions required to mitigate the antimicrobial resistance pandemic are a direct threat to success. We argue that evidence suggests a need to prioritise and support infection prevention interventions (ie, clean water and safe sanitation, increased vaccine coverage, and enhanced infection prevention measures for food production in the Global South contrary to the focus on research and development of new antibiotics in the Global North) and to recalibrate global funding resources to address this need. We call on global leaders to redress the current response, which threatens mitigation of the antimicrobial resistance pandemic.

为了限制不断增加的细菌对抗菌药物的耐药性对健康、食品、环境和地缘政治安全造成的灾难性影响，并确保没有一个国家或地区掉队，需要采取协调一致的全球方法。在本观点中，我们认为，在缓解抗菌药物耐药性大流行所需的行动方面，全球北方和全球南方的资源可用性、需求和优先事项存在差异，这是对成功的直接威胁。我们认为，有证据表明需要优先考虑和支持感染预防干预措施（即清洁水和安全卫生设施、增加疫苗覆盖率以及加强南半球粮食生产的感染预防措施，这与重点关注新抗生素的研发相反）北半球）并重新调整全球资金资源以满足这一需求。我们呼吁全球领导人纠正当前的应对措施，因为当前的应对措施威胁到抗菌素耐药性大流行的缓解。