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Trends in maternal opioid use disorder and neonatal abstinence syndrome in Maine, 2016–2022
Journal of Perinatology ( IF 2.9 ) Pub Date : 2024-01-24 , DOI: 10.1038/s41372-024-01882-x
Julia Dudley , Sarah M. B. Gabrielson , Alane B. O’Connor , Katherine A. Ahrens

Objective

To estimate trends in maternal opioid use disorder (OUD) and neonatal abstinence syndrome (NAS) in Maine using the most recent data available.

Study design

We used hospital discharge data to estimate the annual prevalence of maternal OUD and NAS between 2016 and 2022. In addition, we used birth certificate-linked Medicaid data to estimate related trends among Medicaid enrollees.

Result

From 2016 to 2022, the prevalence of maternal OUD decreased from 35.3 to 18.8 per 1000 deliveries and the prevalence of NAS decreased from 33.2 to 14.0 per 1000 newborns (linear trend p values <0.01). Decreasing trends were also found among Medicaid enrollees.

Conclusion

In Maine between 2016 and 2022, there was a decrease in maternal OUD and NAS diagnoses recorded in administrative datasets. These findings should be interpreted with caution due to changes in how OUD and NAS diagnoses are recorded and COVID-related changes in healthcare utilization.



中文翻译:

2016-2022 年缅因州孕产妇阿片类药物使用障碍和新生儿戒断综合征趋势

客观的

使用最新可用数据估计缅因州孕产妇阿片类药物使用障碍 (OUD) 和新生儿戒断综合征 (NAS) 的趋势。

学习规划

我们使用出院数据来估计 2016 年至 2022 年间孕产妇 OUD 和 NAS 的年度患病率。此外,我们使用与出生证明相关的医疗补助数据来估计医疗补助参与者的相关趋势。

结果

从 2016 年到 2022 年,孕产妇 OUD 患病率从每 1000 名新生儿 35.3 下降到 18.8,NAS 患病率从每 1000 名新生儿 33.2 下降到 14.0(线性趋势p值<0.01)。医疗补助参与者也出现了下降趋势。

结论

2016 年至 2022 年间,缅因州管理数据集中记录的孕产妇 OUD 和 NAS 诊断有所减少。由于 OUD 和 NAS 诊断记录方式的变化以及与新冠病毒相关的医疗保健利用率的变化,应谨慎解释这些发现。

更新日期:2024-01-24
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