With the advancement of globalization, our world is becoming increasingly interconnected. However, this interconnection means that once an infectious disease emerges, it can rapidly spread worldwide. Specifically, viral diseases pose a growing threat to human health. The COVID-19 pandemic has underscored the pressing need for expedited drug development to combat emerging viral diseases. Traditional drug discovery methods primarily rely on random screening and structure-based optimization, and new approaches are required to address more complex scenarios in drug discovery. Emerging antiviral strategies include phase separation and lysosome/exosome targeting. The widespread implementation of these innovative drug design strategies will contribute towards tackling existing viral infections and future outbreaks.

中文翻译：

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彻底改变病毒性疾病治疗：相分离和溶酶体/外泌体靶向作为抗病毒药物研究的新领域和新范例

随着全球化的深入发展，世界的联系日益紧密。然而，这种相互联系意味着传染病一旦出现，就可以在全球范围内迅速传播。具体而言，病毒性疾病对人类健康构成越来越大的威胁。COVID-19 大流行凸显了加快药物开发以对抗新出现的病毒性疾病的迫切需要。传统的药物发现方法主要依赖于随机筛选和基于结构的优化，需要新的方法来解决药物发现中更复杂的情况。新兴的抗病毒策略包括相分离和溶酶体/外泌体靶向。这些创新药物设计策略的广泛实施将有助于应对现有的病毒感染和未来的疫情爆发。