The risk associated with multiple cancers, cardiovascular disease, diabetes, and all-cause mortality is decreased in individuals who meet the current recommendations for physical activity. Therefore, regular exercise remains a cornerstone in the prevention and treatment of non-communicable diseases. An acute bout of exercise results in the coordinated interaction between multiple tissues to meet the increased energy demand of exercise. Over time, the associated metabolic stress of each individual exercise bout provides the basis for long-term adaptations across tissues, including the cardiovascular system, skeletal muscle, adipose tissue, liver, pancreas, gut, and brain. Therefore, regular exercise is associated with a plethora of benefits throughout the whole body, including improved cardiorespiratory fitness, physical function, and glycemic control. Overall, we summarize the exercise-induced adaptations that occur within multiple tissues and how they converge to ultimately improve cardiometabolic health.

中文翻译：

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运动诱导组织特异性适应，增强心脏代谢健康

符合当前体育活动建议的个体与多种癌症、心血管疾病、糖尿病和全因死亡率相关的风险会降低。因此，定期锻炼仍然是预防和治疗非传染性疾病的基石。剧烈的运动会导致多个组织之间的协调相互作用，以满足运动增加的能量需求。随着时间的推移，每次运动的相关代谢压力为跨组织的长期适应提供了基础，包括心血管系统、骨骼肌、脂肪组织、肝脏、胰腺、肠道和大脑。因此，定期锻炼对整个身体有很多好处，包括改善心肺健康、身体机能和血糖控制。总的来说，我们总结了多个组织内发生的运动引起的适应以及它们如何汇聚以最终改善心脏代谢健康。