Health-related social needs (HRSN) are prevalent among cancer patients, associated with substantial negative health consequences, and drive pervasive inequities in cancer incidence, severity, treatment choices and decisions, and outcomes. To address the lack of clinical trial evidence to guide HRSN interventions among cancer patients, the National Cancer Institute Cancer Care Delivery Research Steering Committee convened experts to participate in a Clinical Trials Planning Meeting with the goal of designing studies to screen for and address HRSNs among cancer patients. In this commentary, we discuss the rationale for, and challenges of, designing and testing HRSN interventions in alignment with the National Academy of Sciences, Engineering, and Medicine 5A’s Framework. Evidence for food, housing, utilities, interpersonal safety, and transportation HRSN interventions is analyzed. Evidence regarding HRSNs and delivery of HRSN interventions differ in maturity and applicability to cancer context, with transportation problems having the most maturity and interpersonal safety the least. We offer practical recommendations for HRSN interventions among cancer patients and the caregivers, families, and friends who support their HRSN. Cross-cutting (ie, HRSN-agnostic) recommendations include leveraging navigation (eg, people, technology) to identify, refer, and deliver HRSN interventions; addressing HRSNs through multilevel interventions; and recognizing that HRSNs are states, not traits, that fluctuate over time. HRSN-specific interventions are recommended and pros and cons of addressing more than one HRSN concurrently are characterized. Considerations for collaborating with community partners are highlighted. The need for careful planning, strong partners, and funding is stressed. Finally, we outline a future research agenda to address evidence gaps.

中文翻译：

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满足癌症患者健康相关社会需求的干预措施


与健康相关的社会需求 (HRSN) 在癌症患者中普遍存在，与严重的负面健康后果相关，并导致癌症发病率、严重程度、治疗选择和决策以及结果方面普遍存在不平等。为了解决缺乏临床试验证据来指导癌症患者中 HRSN 干预的问题，国家癌症研究所癌症护理服务研究指导委员会召集了专家参加临床试验计划会议，目的是设计筛查和解决癌症患者中 HRSN 的研究患者。在这篇评论中，我们讨论了根据国家科学、工程和医学 5A 框架设计和测试 HRSN 干预措施的基本原理和挑战。分析了食品、住房、公用事业、人际安全和交通 HRSN 干预措施的证据。关于 HRSN 和 HRSN 干预措施实施的证据在成熟度和对癌症背景的适用性方面有所不同，其中交通问题的成熟度最高，而人际安全问题的成熟度最低。我们为癌症患者以及支持其 HRSN 的护理人员、家人和朋友提供 HRSN 干预的实用建议。跨领域（即与 HRSN 无关）建议包括利用导航（例如人员、技术）来识别、参考和提供 HRSN 干预措施；通过多层次干预措施解决 HRSN 问题；并认识到 HRSN 是随时间波动的状态，而不是特征。建议采取针对 HRSN 的干预措施，并描述同时处理多个 HRSN 的利弊。强调了与社区合作伙伴合作的注意事项。 强调需要仔细规划、强有力的合作伙伴和资金。最后，我们概述了解决证据差距的未来研究议程。