The growing demand for healthy marine lipids and the unmatched supply demand required diversification of their sources. Characterization of starfish oil has shown that it is a new possible source of marine lipids. However, optimized extraction conditions are needed to extract high quality oil. Hence, this study aimed to extract starfish oil using supercritical carbon dioxide (ScCO₂) and optimize the extraction process using response surface methodology (RSM). Temperature, pressure, and ethanol flow rate were the most influential parameters for oil extraction. The RSM model predicted 19.40% and 25.40% for extraction yield and phospholipids content respectively at 40 °C, 350 bar, and 2.61 mL/min of ethanol flow rate. The result of validation extraction showed close agreement with the model. Moreover, the oils were characterized by fatty acid composition, peroxide value, free fatty acid, and tocopherol contents. The current study showed that high-quality lipids could be extracted from underutilized species using ScCO₂ extraction.

对健康海洋脂质不断增长的需求和无与伦比的供应需求需要其来源多样化。海星油的表征表明它是海洋脂质的新的可能来源。然而，需要优化提取条件来提取高质量的油。因此，本研究旨在使用超临界二氧化碳（ScCO ₂）提取海星油，并使用响应面法（RSM）优化提取过程。温度、压力和乙醇流量是对油提取影响最大的参数。RSM 模型预测，在 40 °C、350 bar 和 2.61 mL/min 乙醇流速下，提取率和磷脂含量分别为 19.40% 和 25.40%。验证提取的结果与模型非常吻合。此外，还对油的脂肪酸组成、过氧化值、游离脂肪酸和生育酚含量进行了表征。_{目前的研究表明，可以使用 ScCO 2}萃取从未充分利用的物种中提取高质量的脂质。