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Cytotoxic Th1 cells mushroom after fungal exposures in Crohn’s disease
Immunity ( IF 32.4 ) Pub Date : 2023-12-12 , DOI: 10.1016/j.immuni.2023.11.012
Martin Stražar , Ramnik J. Xavier

Fungi are consistently enriched in inflamed intestines, with elusive effects on host immunity. In a recent issue of Nature Medicine, Martini et al. identify a subset of Th1 cells able to lyse the epithelium, enriched in Crohn’s disease patient samples after fungal exposure.



中文翻译:


克罗恩病真菌暴露后细胞毒性 Th1 细胞迅速增多



真菌在发炎的肠道中持续富集,对宿主免疫力产生难以捉摸的影响。在最近一期的《自然医学》杂志上,Martini 等人。鉴定出能够裂解上皮的 Th1 细胞子集,这些细胞在真菌暴露后在克罗恩病患者样本中富集。

更新日期:2023-12-16
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