Mounting evidence suggests that physical exercise protects the brain against neurodegenerative disease. In a recent paper in Neuron, Kim et al. reported that the exercise-induced hormone irisin curbs amyloid-β buildup by promoting secretion of astrocyte-derived neprilysin. These findings may help explain the neuroprotection by irisin and exercise in Alzheimer’s disease.

中文翻译：

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鸢尾素限制阿尔茨海默病中β淀粉样蛋白的积累

越来越多的证据表明，体育锻炼可以保护大脑免受神经退行性疾病的侵害。 Kim 等人最近在 Neuron 上发表了一篇论文。报道称，运动诱发的激素鸢尾素通过促进星形胶质细胞衍生的脑啡肽酶的分泌来抑制淀粉样蛋白-β的积累。这些发现可能有助于解释鸢尾素和运动对阿尔茨海默病的神经保护作用。