The panoramic characteristics of human–machine interfaces (HMIs) have prompted the needs to update the biotechnology community with the recent trends, developments, and future research direction toward next-generation bioelectronics. Bioinspired materials are promising for integrating various bioelectronic devices to realize HMIs. With the advancement of scientific biotechnology, state-of-the-art bioelectronic applications have been extensively investigated to improve the quality of life by developing and integrating bioinspired nanoplatforms in HMIs. This review highlights recent trends and developments in the field of biotechnology based on bioinspired nanoplatforms by demonstrating recently explored materials and cutting-edge device applications. Section 1 introduces the recent trends and developments of bioinspired nanomaterials for HMIs. Section 2 reviews various flexible, wearable, biocompatible, and biodegradable nanoplatforms for bioinspired applications. Section 3 furnishes recently explored substrates as carriers for advanced nanomaterials in developing HMIs. Section 4 addresses recently invented biomimetic neuroelectronic, nanointerfaces, biointerfaces, and nano/microfluidic wearable bioelectronic devices for various HMI applications, such as healthcare, biopotential monitoring, and body fluid monitoring. Section 5 outlines designing and engineering of bioinspired sensors for HMIs. Finally, the challenges and opportunities for next-generation bioinspired nanoplatforms in extending the potential on HMIs are discussed for a near-future scenario. We believe this review can stimulate the integration of bioinspired nanoplatforms into the HMIs in addition to wearable electronic skin and health-monitoring devices while addressing prevailing and future healthcare and material-related problems in biotechnologies.

人机界面（HMI）的全景特征促使生物技术界需要更新下一代生物电子学的最新趋势、发展和未来研究方向。仿生材料有望集成各种生物电子设备以实现 HMI。随着科学生物技术的进步，最先进的生物电子应用已得到广泛研究，通过在人机界面中开发和集成仿生纳米平台来提高生活质量。本综述通过展示最近探索的材料和尖端设备应用，突出了基于仿生纳米平台的生物技术领域的最新趋势和发展。第 1 节介绍了用于 HMI 的仿生纳米材料的最新趋势和发展。第 2 部分回顾了用于仿生应用的各种灵活、可穿戴、生物相容性和可生物降解的纳米平台。第 3 节提供了最近探索的基材作为开发 HMI 中先进纳米材料的载体。第 4 节介绍了最近发明的仿生神经电子、纳米接口、生物接口和纳米/微流体可穿戴生物电子设备，用于各种 HMI 应用，例如医疗保健、生物电势监测和体液监测。第 5 节概述了用于 HMI 的仿生传感器的设计和工程。最后，讨论了在不久的将来场景中下一代仿生纳米平台在扩展 HMI 潜力方面面临的挑战和机遇。我们相信，除了可穿戴电子皮肤和健康监测设备之外，这次审查还可以促进仿生纳米平台与 HMI 的集成，同时解决生物技术中当前和未来的医疗保健和材料相关问题。