Human development is a highly coordinated process, with any abnormalities during the early embryonic stages that can often have detrimental consequences. The complexity and nuances of human development underpin its significance in embryo research. However, this research is often hindered by limited availability and ethical considerations associated with the use of donated blastocysts from in vitro fertilization (IVF) surplus. Human blastoids offer promising alternatives as they can be easily generated and manipulated in the laboratory while preserving key characteristics of human blastocysts. In this way, they hold the potential to serve as a scalable and ethically permissible resource in embryology research. By utilizing such human embryo models, we can establish a transformative platform that complements the study with IVF embryos, ultimately enhancing our understanding of human embryogenesis.

人类发育是一个高度协调的过程，早期胚胎阶段的任何异常通常都会产生有害的后果。人类发育的复杂性和细微差别巩固了其在胚胎研究中的重要性。然而，这项研究常常受到有限的可用性和与使用体外受精（IVF）剩余的捐赠囊胚相关的伦理考虑的阻碍。人类胚泡提供了有前途的替代品，因为它们可以在实验室中轻松生成和操作，同时保留人类胚泡的关键特征。通过这种方式，它们有潜力成为胚胎学研究中可扩展且道德允许的资源。通过利用此类人类胚胎模型，我们可以建立一个变革平台，补充体外受精胚胎的研究，最终增强我们对人类胚胎发生的理解。