Activation of endogenous glucocorticoids by HSD11B1 inhibits the antitumor immune response in renal cancer,OncoImmunology

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Activation of endogenous glucocorticoids by HSD11B1 inhibits the antitumor immune response in renal cancer
OncoImmunology ( IF 7.2 ) Pub Date : 2023-11-30 , DOI: 10.1080/2162402x.2023.2286820
Hélène Poinot _{1,

2} , Eloïse Dupuychaffray _{1,

2} , Grégoire Arnoux ₃ , Montserrat Alvarez _{1,

2} , Jérémie Tachet _{1,

2} , Ounss Ezzar _{1,

2} , Jonathan Moore ₄ , Olivia Bejuy ₅ , Eulalia Olesti _{1,

2} , Gioele Visconti _{1,

2} , Víctor González-Ruiz _{1,

2} , Serge Rudaz _{1,

2} , Jean-Christophe Tille ₆ , Clarissa D. Voegel ₇ , Patrycja Nowak-Sliwinska _{1,

2,

4} , Carole Bourquin _{1,

2,

8} , Aurélien Pommier _{1,

2}

Affiliation

Although immune-based therapies have revolutionized the management of cancer, novel approaches are urgently needed to improve their outcome. We investigated the role of endogenous steroids in the r...

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