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Alzheimer’s defense: brain CD8+ T cells in action
Trends in Immunology ( IF 16.8 ) Pub Date : 2023-11-07 , DOI: 10.1016/j.it.2023.10.012
Dan Hu 1
Affiliation  

In a remarkable new study, Su et al. have shown that a specific subpopulation of CD8+ T cells, attracted to brain lesion sites and expanded via microglia-CD8+ T cell CXCL16-CXCR6 intercellular communication, can curb Alzheimer’s disease (AD)-related pathology in mouse models.



中文翻译:

阿尔茨海默病防御:大脑 CD8+ T 细胞的作用

在一项引人注目的新研究中,Su等人。研究表明,特定的 CD8 + T 细胞亚群被吸引到大脑病变部位并通过小胶质细胞-CD8 + T 细胞 CXCL16-CXCR6 细胞间通讯进行扩展,可以抑制小鼠模型中与阿尔茨海默病 (AD) 相关的病理。

更新日期:2023-11-07
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