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Shaping microbiome function with a human milk-oligosaccharide synbiotic
Trends in Endocrinology & Metabolism ( IF 10.9 ) Pub Date : 2023-11-07 , DOI: 10.1016/j.tem.2023.10.007
Ethel Closa 1 , Loudon Herold 1 , Matthew T Sorbara 1
Affiliation  

In a recent article, Button and colleagues demonstrate that human milk oligosaccharides create a nutrient niche that supports reversible colonization by Bifidobacterium infantis. Using this tunable system, they assessed the impact of B. infantis on microbiome recovery after antibiotic treatment. Overall, this work highlights synbiotics as a useful approach for developing live biotherapeutic products (LBPs).



中文翻译:

用母乳低聚糖合生元塑造微生物组功能

在最近的一篇文章中,巴顿和同事证明,母乳寡糖创造了一个营养生态位,支持婴儿双歧杆菌的可逆定植。利用这种可调系统,他们评估了婴儿双歧杆菌对抗生素治疗后微生物组恢复的影响。总体而言,这项工作强调了合生元是开发活生物治疗产品(LBP)的有用方法。

更新日期:2023-11-08
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