We read with interest the recent article ‘MOG antibody-associated encephalitis in adult: clinical phenotypes and outcomes’ by Lee et al 1 and the letter to the editor entitled ‘Acute haemorrhagic leucoencephalitis as clinical manifestation of MOG antibody-associated disease’ by Skarsta et al .2 In the first article, the authors illustrate three different phenotypes of MOG (myelin oligodendrocyte glycoprotein) antibody-associated encephalitis in 40 patients, including acute disseminated encephalomyelitis (ADEM) in 17 patients. They highlight the favourable outcome of these encephalitis cases following immunosuppressive treatment.1 Conversely, the second article reports on the case of a patient with acute haemorrhagic leucoencephalitis (also known as Hurst encephalitis, which is a haemorrhagic variant of ADEM) associated with MOG antibodies, with a highly aggressive clinical course and unfavourable prognosis.2 We would like to raise awareness of another unfavourable presentation of MOG antibody-associated disease (MOGAD), namely haemorrhagic myelitis. We report on the case of a patient in their 30s who presented in May 2018 with paraparesis that worsened over 2 days, …

中文翻译：

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出血性脊髓炎是 MOG 抗体相关疾病的一种表现

我们饶有兴趣地阅读了 Lee 等人最近发表的文章“成人 MOG 抗体相关脑炎：临床表型和结果”1 以及 Skarsta 等人写给编辑的题为“急性出血性白质脑炎作为 MOG 抗体相关疾病的临床表现”的信al .2 在第一篇文章中，作者阐述了 40 名患者的 MOG（髓磷脂少突胶质细胞糖蛋白）抗体相关脑炎的三种不同表型，其中 17 名患者患有急性播散性脑脊髓炎 (ADEM)。他们强调了这些脑炎病例在免疫抑制治疗后取得了良好的结果。1 相反，第二篇文章报道了一名与 MOG 抗体相关的急性出血性白质脑炎（也称为 Hurst 脑炎，是 ADEM 的出血性变体）患者的病例，具有高度侵袭性的临床病程和不良的预后。2我们希望提高人们对 MOG 抗体相关疾病 (MOGAD) 的另一种不利表现的认识，即出血性脊髓炎。我们报告了一名 30 多岁患者的病例，该患者于 2018 年 5 月就诊，出现截瘫，并在 2 天内病情恶化，……