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A systematic review and meta-analysis of intensive treatment options for adults with eating disorders
Clinical Psychology Review ( IF 12.8 ) Pub Date : 2023-10-26 , DOI: 10.1016/j.cpr.2023.102354
Kathleen de Boer 1 , Catherine Johnson 2 , Tracey D Wade 2 , Marcela Radunz 2 , Anne Nileshni Fernando 1 , Jennifer Babb 3 , Simon Stafrace 3 , Gemma Sharp 4
Affiliation  

Eating disorders (EDs) are complex conditions with one of the highest mortality rates among psychiatric illnesses. While outpatient evidence-based treatments for EDs in adults exist, there is often utilisation of more intensive interventions as part of treatment. However, a comprehensive analysis of the impacts of intensive treatment (inpatient, residential and day program) on physical and psychosocial outcomes is lacking. Thus, the current systematic review and meta-analysis aimed to investigate the effectiveness of intensive treatments in adults with EDs for the outcomes of body mass index (BMI), disordered eating, depression, and quality of life, as well as a moderation analysis investigating a range of clinical characteristics. Overall, 62 studies were included in the meta-analysis. The results revealed that intensive treatment in adults yielded significant improvements in BMI (for underweight patients), disordered eating, depression, and quality of life. Treatment setting, length of stay and geographical region of the study all served as moderators for disordered eating and depression. Nevertheless, given the high heterogeneity in the meta- and moderation analyses, these results should be interpreted with caution. Future high-quality research is needed to determine the most beneficial elements of intensive treatment (compared to outpatient) in adults with EDs.



中文翻译:

对患有饮食失调的成人强化治疗方案的系统回顾和荟萃分析

饮食失调(ED)是一种复杂的疾病,是精神疾病中死亡率最高的疾病之一。虽然针对成人 ED 的门诊循证治疗存在,但通常会采用更强化的干预措施作为治疗的一部分。然而,缺乏对强化治疗(住院、住院和日间治疗)对身体和心理社会结果影响的全面分析。因此,当前的系统评价和荟萃分析旨在调查成人 ED 强化治疗对体重指数 (BMI)、饮食失调、抑郁和生活质量结果的有效性,以及调查的调节分析一系列的临床特征。总体而言,荟萃分析纳入了 62 项研究。结果显示,成人强化治疗可显着改善体重指数(体重过轻的患者)、饮食失调、抑郁症和生活质量。治疗环境、住院时间和研究的地理区域都是饮食失调和抑郁症的调节因素。然而,鉴于荟萃分析和调节分析的高度异质性,这些结果应谨慎解释。未来需要进行高质量的研究来确定对成人 ED 的强化治疗(与门诊患者相比)最有益的要素。

更新日期:2023-10-26
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