Informal caregivers are the primary source of support for adults with chronic conditions and disabilities. Empirical research highlights chronic stress and other risks of adverse outcomes of caregiving. Acceptance and Commitment Therapy (ACT) is an emerging evidenced-based practice that shows promise in improving an array of outcomes, theoretically by increasing psychological flexibility as the primary process of change. Research has begun to evaluate ACT among informal caregivers of adult populations, and a systematic review is now needed to summarise this evidence base.

Electronic searches from five databases, including PubMed, PsycInfo, Embase, CINAHL, and Cochrane Library, yielded an initial 7896 hits, which after screening for inclusion criteria, resulted in 21 clinical trials. Studies were coded to synthesise the feasibility, effectiveness, and quality of evidence. Findings show that ACT was reported to be largely feasible and acceptable. However, the efficacy of ACT was mixed, with a more consistent pattern for informal caregivers of people with dementia.

Several methodological quality issues limited the findings. However, theoretical synthesis and preliminary evidence support the promising effect of ACT in subgroups of informal caregivers. Research on the process of change, as well as larger-scale, methodologically rigorous trials, are needed to consolidate these findings.

非正式护理人员是患有慢性病和残疾的成年人的主要支持来源。实证研究强调了护理带来的慢性压力和其他不良后果的风险。接受与承诺疗法（ACT）是一种新兴的循证实践，理论上通过增加心理灵活性作为改变的主要过程，有望改善一系列结果。研究已开始评估成人非正式护理人员的 ACT，现在需要进行系统审查来总结这一证据基础。

从 PubMed、PsycInfo、Embase、CINAHL 和 Cochrane Library 等 5 个数据库进行电子检索，初步获得 7896 条结果，在筛选纳入标准后，产生了 21 项临床试验。研究被编码以综合证据的可行性、有效性和质量。研究结果表明，ACT 基本上是可行且可接受的。然而，ACT 的疗效参差不齐，对于痴呆症患者的非正式护理人员来说，其效果更为一致。

一些方法学质量问题限制了研究结果。然而，理论综合和初步证据支持 ACT 在非正式护理人员亚群体中的良好效果。需要对变化过程进行研究，以及更大规模、方法上严格的试验来巩固这些发现。