Our research focused on defining and characterizing parieto-frontal circuits for specific actions in primates. Part of the posterior parietal cortex is divided into eight or more domains where electrical stimulation evokes a meaningful complex movement. Domains in the posterior parietal cortex compete with each other over excitatory connections that activate inhibitory neurons, while selectively activating functionally matched domains in the premotor cortex and motor cortex. Thus, the selection process involves competition and cooperation between domains over three different regions of cortex. In addition, projections from functionally matched domains in motor regions converge in the matrix of the striatum, whereas projections from different functionally unmatched domains are separate. Thus, the projections of action-specific domains include the basal ganglia, where actions can be permitted or blocked.

我们的研究重点是定义和表征灵长类动物特定行为的顶额叶回路。后顶叶皮层的一部分分为八个或更多区域，电刺激在其中引发有意义的复杂运动。后顶叶皮层中的域在激活抑制性神经元的兴奋性连接上相互竞争，同时选择性地激活前运动皮层和运动皮层中功能匹配的域。因此，选择过程涉及皮层三个不同区域的域之间的竞争与合作。此外，来自运动区功能匹配域的投影会聚在纹状体的矩阵中，而来自不同功能不匹配域的投影是分开的。因此，特定动作域的投影包括基底神经节，其中可以允许或阻止动作。