Older adults commonly end up on many medications. Deprescribing is an important part of individualizing care for older adults. It is an opportunity to discuss treatment options and revisit medications that may not have been reassessed in many years. A large evidence base exists in the field, suggesting that deprescribing is feasible and safe, though questions remain about the potential clinical benefits. Deprescribing research faces a myriad of challenges, such as identifying and employing the optimal outcome measures. Further, there is uncertainty about which deprescribing approaches are likely to be most effective and in what contexts. Evidence on barriers and facilitators to deprescribing has underscored how deprescribing in routine clinical practice can be complex and challenging. Thus, finding practical, sustainable ways to implement deprescribing is a priority for future research in the field.

中文翻译：

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老年人的多重用药和停用处方

老年人通常最终会服用多种药物。取消处方是老年人个体化护理的重要组成部分。这是一个讨论治疗方案和重新审视多年来可能没有重新评估的药物的机会。该领域存在大量证据基础，表明取消处方是可行且安全的，但潜在的临床益处仍存在疑问。取消处方研究面临着无数挑战，例如确定和采用最佳结果衡量标准。此外，对于哪些去处方方法可能最有效以及在什么情况下最有效还存在不确定性。关于取消处方的障碍和促进因素的证据强调了常规临床实践中取消处方的复杂性和挑战性。因此，寻找实用、可持续的方法来实施取消处方是该领域未来研究的首要任务。