Proteomic-based approaches are increasingly being used to assess alterations in the proteomic profile of seminal plasma in men with infertility with the aim to characterize the molecular pathways responsible for altered spermatogenesis and identify potential biomarkers. However, testes are responsible for a limited portion of the seminal plasma proteome, and limited information is available about dysregulations in the testicular microenvironment.

中文翻译：

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基于蛋白质组学的睾丸间质液分析

基于蛋白质组学的方法越来越多地用于评估不育男性精浆蛋白质组学谱的变化，目的是表征导致精子发生改变的分子途径并识别潜在的生物标志物。然而，睾丸负责精浆蛋白质组的有限部分，并且关于睾丸微环境失调的信息有限。