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Allogeneic haematopoietic cell transplants as dynamical systems: influence of early-term immune milieu on long-term T-cell recovery
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2023-07-13 , DOI: 10.1002/cti2.1458
Viktoriya Zelikson 1 , Roy Sabo 2 , Myrna Serrano 3 , Younus Aqeel 1 , Savannah Ward 1 , Taha Al Juhaishi 1 , May Aziz 4 , Elizabeth Krieger 5 , Gary Simmons 1 , Catherine Roberts 1 , Jason Reed 6 , Gregory Buck 2 , Amir Toor 1, 7
Affiliation  

Immune recovery following haematopoietic cell transplantation (HCT) functions as a dynamical system. Reducing the duration of intense immune suppression and augmenting antigen presentation has the potential to optimise T-cell reconstitution, potentially influencing long-term outcomes.

中文翻译:

作为动力系统的同种异体造血细胞移植:早期免疫环境对长期 T 细胞恢复的影响

造血细胞移植(HCT)后的免疫恢复作为一个动力系统发挥作用。减少强烈免疫抑制的持续时间和增强抗原呈递有可能优化 T 细胞重建,从而可能影响长期结果。
更新日期:2023-07-14
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