Microbubble dispersions are now commonly deployed in industrial applications ranging from bioprocesses to chemical reaction engineering, at full scale. There are five major classes of microbubble generation devices that are scalable. In recent years, some of these approaches have been explicitly studied for the influence of wetting properties on microbubble performance, for which the major proxy is the bubble-size distribution. In this piece, the methodologies for inferring bubble-size distribution are explored, with several recent advances as well as their potential pitfalls. Subsequently, studies where microbubble generation has been under investigation for wetting effects are assessed and in some cases, those that were not allowed the deduction that wetting is a significant factor. Two particular studies are highlighted: (i) systematic variation of wetting effects within a venturi with removable walls substituted with coated walls of known contact angle with hydrodynamic cavitation induced microbubbles and (ii) variation of ionic liquids with staged fluidic oscillation before steady flow. The first study shows that even in scenarios where high inertial effects would be expected to dominate, wetting influences are significant. The second study shows that transient effects are strongly influenced by both imbibition into pores and surface wetting but that viscous resistance is always a key factor. From the exploration of these recent studies, specific recommendations are made about how to assess the influence of wetting in those mechanisms/devices where it has not been explicitly studied, via deduction from those mechanisms/devices where the effects are demonstrably significant and indeed in some cases, controlling. In study (ii), which is the first to blow micro/bubbles into ionic liquids, wetting and transient effects are reasonable for between 25% and 50% reduction in average bubble size, although up to 70% reduction is observable when viscous effects are dominant, relative to the control of steady flow with the same pressure drop. Indeed, staging transient operations shows both bubble-size reduction and increased volumetric throughput are simultaneously possible.

微泡分散体现在广泛应用于从生物工艺到化学反应工程的工业应用中。可扩展的微气泡发生设备主要有五类。近年来，其中一些方法已经明确研究了润湿特性对微泡性能的影响，其中主要指标是气泡尺寸分布。在本文中，探讨了推断气泡尺寸分布的方法，以及一些最新进展及其潜在缺陷。随后，对微泡产生的润湿效应进行了研究，在某些情况下，那些不允许推断润湿是一个重要因素的研究进行了评估。强调了两项特别的研究：(i) 文丘里管内润湿效果的系统变化，其中可移动壁被已知接触角的涂层壁取代，并具有水动力空化引起的微泡；(ii) 离子液体在稳定流动之前随着分阶段流体振荡的变化。第一项研究表明，即使在高惯性效应占主导地位的情况下，润湿影响也很显着。第二项研究表明，瞬态效应受到孔隙吸入和表面润湿的强烈影响，但粘性阻力始终是关键因素。通过对这些最近研究的探索，提出了关于如何评估润湿对那些尚未明确研究的机制/设备的影响的具体建议，通过从那些效果明显显着并且实际上在某些情况下具有控制作用的机制/装置中进行推论。在第一个将微气泡吹入离子液体的研究 (ii) 中，相对于相同压降的稳定流控制，润湿和瞬态效应对于平均气泡尺寸减少 25% 至 50% 是合理的，尽管当粘性效应占主导地位时可观察到高达 70% 的减少。事实上，分阶段瞬态操作表明气泡尺寸减小和体积吞吐量增加是同时可能的。尽管当粘性效应占主导地位时，相对于相同压降的稳定流控制，可以观察到高达 70% 的减少。事实上，分阶段瞬态操作表明气泡尺寸减小和体积吞吐量增加是同时可能的。尽管当粘性效应占主导地位时，相对于相同压降的稳定流控制，可以观察到高达 70% 的减少。事实上，分阶段瞬态操作表明气泡尺寸减小和体积吞吐量增加是同时可能的。