The preparation of plant protein-based adhesives is one of the potential strategies to mitigate environmental pollution. In this work, the organic-inorganic copolymerization of calcium phosphate oligomer and soy protein was performed by adopting the concept of organic-inorganic polymerization and the physics of polymer adsorption to eliminate the interphase boundary, preparing an adhesive layer with continuous and uniform network structure without using chemical cross-linkers. The participation of ionic and hydrogen bonds improved the mechanical strength. In addition, the Laponite with anisotropic charge distribution was introduced into the cross-linking network to increase the density and cohesion of cross-linking and further improve the bonding performance without complex chemical synthesis. The modified adhesive had an optimum wet shear strength of 1.01 MPa, and excellent water resistance (85.7 % residue rate). The modified adhesive shows good cell compatibility plus flame retardancy. Overall, this biomimetic study has excellent promises for the design of protein-based adhesives with desirable properties for engineering applications.

制备植物蛋白基粘合剂是减轻环境污染的潜在策略之一。本工作采用有机-无机聚合的概念和高分子吸附的物理原理，进行磷酸钙低聚物与大豆蛋白的有机-无机共聚，消除了磷酸钙低聚物与大豆蛋白的有机-无机共聚。相界面，在不使用化学交联剂的情况下制备具有连续和均匀网络结构的粘合剂层。离子键和氢键的参与提高了机械强度。此外，在交联网络中引入电荷分布各向异性的Laponite，增加交联的密度和内聚力，进一步提高键合性能，无需复杂的化学合成。改性后的粘合剂具有 1.01 MPa 的最佳湿剪切强度和出色的耐水性（85.7% 的残留率）。改性粘合剂显示出良好的电池相容性和阻燃性。总的来说，这项仿生研究对于设计具有工程应用所需特性的蛋白质基粘合剂具有极好的前景。