An inherently challenging enantioselective direct reductive amination reaction under mild and operationally simple transfer hydrogenative conditions was developed using a rationally designed, chiral pyridine-derived half-sandwich iridium catalyst. The reaction was compatible with various functional groups and coordinative heterocycles.

中文翻译：

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使用手性吡啶衍生的半夹心催化剂进行无添加剂转移氢化直接不对称还原胺化

使用合理设计的手性吡啶衍生的半夹心铱催化剂，在温和且操作简单的转移氢化条件下开发了一种固有挑战性的对映选择性直接还原胺化反应。该反应与各种官能团和配位杂环相容。