Molybdenite is the main source of molybdenum which is widely used in industry. Due to its excellent natural floatability, it is urgent to develop selective depressants, which is the key to achieve the flotation separation of molybdenite from other sulfide minerals such as chalcopyrite, galena and pyrite. In this work, a thiazole depressant 2,4-thiazolidinedione (CSD7) is developed based on the selective chelation of heteroatoms to Cu²⁺, Pb²⁺ and Fe²⁺. The flotation tests of single and mixed minerals confirm that CSD7 can achieve an efficient separation of molybdenite from chalcopyrite, galena and pyrite in a collector-free flotation system. Under the concentration of CSD7 with 5 × 10⁻⁴ mol/L and pulp pH of 7, the grades of molybdenite concentrate are higher than 50%, and the corresponding recoveries are higher than 80%. The Fourier Transform Infrared Spectroscopy (FT-IR) and electrochemical tests indicate that CSD7 can adsorb onto the surfaces of chalcopyrite, galena and pyrite, but can hardly adsorb onto the surface of molybdenite. CSD7 chelates with Cu²⁺, Pb²⁺ and Fe²⁺ on the surfaces of chalcopyrite, galena and pyrite through the four-membered ring formed by the bonds of −S−M²⁺ and =O−M²⁺. Moreover, the contact angle measurements also manifest that CSD7 selectively strengthen the hydrophilicity of the surfaces of chalcopyrite, galena and pyrite rather than molybdenite. The simply synthesized, low-cost and green CSD7 has a great potential in the separation of molybdenum from other sulfide minerals in flotation plant.

辉钼矿是工业上广泛使用的钼的主要来源。由于其优异的天然可浮性，迫切需要开发选择性抑制剂，这是实现辉钼矿与黄铜矿、方铅矿和黄铁矿等其他硫化矿物浮选分离的关键。^{在这项工作中，基于杂原子与 Cu 2+}、Pb ²⁺和 Fe ²⁺的选择性螯合，开发了一种噻唑抑制剂 2,4-噻唑烷二酮 (CSD7) 。单一和混合矿物的浮选试验证实，CSD7 可以在无捕收剂浮选系统中实现辉钼矿与黄铜矿、方铅矿和黄铁矿的有效分离。在 CSD7 浓度为 5 × 10 ^-4mol/L和矿浆pH为7，辉钼精矿品位高于50%，相应回收率高于80%。傅里叶变换红外光谱（FT-IR）和电化学测试表明，CSD7可以吸附在黄铜矿、方铅矿和黄铁矿的表面，但几乎不能吸附在辉钼矿的表面。^{CSD7通过-S- M 2+}和=O-M ²⁺键形成的四元环与黄铜矿、方铅矿和黄铁矿表面的Cu 2+ 、^{Pb 2+}和Fe 2+ 螯合. 此外，接触角测量还表明，CSD7 选择性地增强了黄铜矿、方铅矿和黄铁矿表面的亲水性，而不是辉钼矿。合成简单、成本低、绿色环保的CSD7在浮选厂将钼与其他硫化矿物分离方面具有巨大潜力。