Accompanying the increasing translational impact of immunotherapeutic strategies to treat and prevent disease has been a broadening interest across both bioscience and bioengineering in the lymphatic system. Herein, the lymphatic system physiology, ranging from its tissue structures to immune functions and effects, is described. Design principles and engineering approaches to analyze and manipulate this tissue system in nanoparticle-based drug delivery applications are also elaborated.

中文翻译：

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用于将生理学信息药物输送至淋巴系统的纳米技术


随着免疫治疗策略对治疗和预防疾病的转化影响不断增加，人们对淋巴系统的生物科学和生物工程的兴趣也日益广泛。本文描述了淋巴系统的生理学，从其组织结构到免疫功能和作用。还详细阐述了在纳米颗粒药物输送应用中分析和操纵该组织系统的设计原理和工程方法。