This article discusses psychosocial interventions in the contexts they are meant to be delivered. Prevention and intervention science often follow the linear pathway of preclinical or pre-intervention research-efficacy trials, effectiveness trials, and implementation studies-with the assessment of translation into public and population health impact occurring at the end. This linear translational pathway follows stages developed for ascertaining safe, efficacious, and effective dosages for biological compounds. This approach has created limitations in the need to rapidly deploy complex, multi-component, multilevel approaches to change behavior and improve health into widespread practice for diverse clinical and public health settings. While it is important to use efficacy trials when safety is yet to be established, when the risks are identified to be low, as is often the case for psychosocial interventions, we can go faster to achieve equitable population health impact. The authors recommend that clinical trialists engaged in intervention development incorporate two considerations in the next generation of prevention and intervention research. First, consider moving right to effectiveness or pragmatic trials, as the most valid test of an intervention is the est of that intervention in the context(s) in which it is intended. Second, when designing effectiveness studies, consider investigating questions related to both effectiveness (i.e., does the intervention improve clinical outcomes) and implementation (i.e., what supports are needed to deploy the intervention routinely in that context) to accelerate impact. As a matter of both ethics and equity, there is a need to expedite the research-to-practice pipeline at a pace faster than is made available through current approaches. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

中文翻译：

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在预期的背景下测试社会心理干预措施。

本文讨论了心理社会干预措施的目的。预防和干预科学通常遵循临床前或干预前研究的线性路径——功效试验、有效性试验和实施研究——最后评估转化为公共和人口健康影响。这种线性翻译途径遵循为确定生物化合物的安全、有效和有效剂量而开发的阶段。这种方法限制了快速部署复杂的、多组件的、多层次的方法来改变行为和改善健康，以广泛应用于不同的临床和公共卫生环境。虽然在安全性尚未确定的情况下使用功效试验很重要，但当风险被确定为较低时（心理社会干预措施经常出现这种情况），我们可以更快地实现公平的人口健康影响。作者建议从事干预开发的临床试验人员在下一代预防和干预研究中考虑两个因素。首先，考虑转向有效性或务实试验，因为干预措施最有效的测试是干预措施在其预期背景下的最佳测试。其次，在设计有效性研究时，考虑调查与有效性（即干预措施是否改善临床结果）和实施（即在这种情况下常规部署干预措施需要哪些支持）相关的问题，以加速影响。出于道德和公平的考虑，有必要以比当前方法更快的速度加快研究到实践的进程。（PsycInfo 数据库记录 (c) 2023 APA，保留所有权利）。