Amblyopia is a disorder of neurodevelopment that occurs when there is discordant binocular visual experience during the first years of life. While treatments are effective in improving visual acuity, there are significant individual differences in response to treatment that cannot be attributed solely to difference in adherence. In this considerable variability in response to treatment, we argue that treatment outcomes might be optimized by utilizing deep phenotyping of amblyopic deficits to guide alternative treatment choices. In addition, an understanding of the broader knock-on effects of amblyopia on developing visually-guided skills, self-perception, and quality of life will facilitate a whole person healthcare approach to amblyopia.

弱视是一种神经发育障碍，当在生命的最初几年中双眼视觉体验不一致时就会发生。虽然治疗可有效提高视力，但对治疗的反应存在显着的个体差异，不能仅归因于依从性差异。在这种对治疗反应的相当大的可变性中，我们认为可以通过利用弱视缺陷的深度表型来指导替代治疗选择来优化治疗结果。此外，了解弱视对发展视觉引导技能、自我认知和生活质量的更广泛连锁影响，将促进针对弱视的全人医疗保健方法。