This review article describes the current status of data archiving and computational infrastructure in the field of genomic medicine, focusing primarily on the situation in Japan. I begin by introducing the status of supercomputer operations in Japan, where a high-performance computing infrastructure (HPCI) is operated to meet the diverse computational needs of science in general. Since this HPCI consists of supercomputers of various architectures located across the nation connected via a high-speed network, including supercomputers specialized in genome science, the status of its response to the explosive increase in genomic data, including the International Nucleotide Sequence Database Collaboration (INSDC) data archive, is explored. Separately, since it is clear that the use of commercial cloud computing environments needs to be promoted, both in light of the rapid increase in computing demands and to support international data sharing and international data analysis projects, I explain how the Japanese government has established a series of guidelines for the use of cloud computing based on its cybersecurity strategy and has begun to build a government cloud for government agencies. I will also carefully consider several other issues of user concern. Finally, I will show how Japan’s major cloud computing infrastructure is currently evolving toward a multicloud and hybrid cloud configuration.

这篇评论文章描述了基因组医学领域数据归档和计算基础设施的现状，主要关注日本的情况。我首先介绍日本的超级计算机运行状况，其中运行高性能计算基础设施 (HPCI) 以满足一般科学的多样化计算需求。由于这个 HPCI 由位于全国各地的各种架构的超级计算机组成，这些超级计算机通过高速网络连接，包括专门从事基因组科学的超级计算机，其对基因组数据爆炸性增长的响应状态，包括国际核苷酸序列数据库协作（INSDC） ) 数据存档，进行了探索。另外，由于很明显需要推广商业云计算环境的使用，鉴于计算需求的快速增长以及支持国际数据共享和国际数据分析项目，我解释了日本政府如何基于其网络安全战略制定了一系列云计算使用指南，并开始构建政府机构的政府云。我也会仔细考虑用户关心的其他几个问题。最后，我将展示日本的主要云计算基础设施目前如何向多云和混合云配置发展。我解释了日本政府如何根据其网络安全战略制定了一系列云计算使用指南，并开始为政府机构构建政府云。我也会仔细考虑用户关心的其他几个问题。最后，我将展示日本的主要云计算基础设施目前如何向多云和混合云配置发展。我解释了日本政府如何根据其网络安全战略制定了一系列云计算使用指南，并开始为政府机构构建政府云。我也会仔细考虑用户关心的其他几个问题。最后，我将展示日本的主要云计算基础设施目前如何向多云和混合云配置发展。