Cell公布2016年度最佳文章

（图片来源：Cell）

近日，Cell杂志公布了2016年度10篇最佳论文和4篇最佳综述。

最佳文章包括：（1）Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming；（2）Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma；（3）Progressive Loss of Function in a Limb Enhancer during Snake Evolution；（4）Domestication and Divergence of Saccharomyces cerevisiae Beer Yeasts；（5）Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise；（6）Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring；（7）Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery；（8）Programmable RNA Tracking in Live Cells with CRISPR/Cas9；（9）High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing；（10）Ultra-High Resolution 3D Imaging of Whole Cells。

最佳综述包括：（1）Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering；（2）The Basis of Oncoimmunology；（3）Modeling Development and Disease with Organoids；（4）The Cellular Phase of Alzheimer’s Disease。

http://cell_bestof2016.elsevierdigitaledition.com/