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The importance of HPV16 in anal cancer prevention
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2017-11-17 , DOI: 10.1016/s1473-3099(17)30683-7
Ulrike Wieland , Alexander Kreuter

Like cervical cancer, anal cancer and its direct precursor lesion, high-grade anal intraepithelial neoplasia (AIN), are caused by persistent infections with human papillomaviruses (HPV).1 The natural history of HPV in cervical cancer has been comprehensively investigated. In the more than 40 HPV types infecting the anogenital tract, high-risk HPV-types and possible or probable high-risk types for the development of cervical cancer have been defined.2 Cervical cancer is preventable by regular screening.

中文翻译:

HPV16在预防肛门癌中的重要性

像宫颈癌一样,肛门癌及其直接的前体病变(高级别的肛门上皮内瘤变(AIN))是由人类乳头瘤病毒(HPV)持续感染引起的。1已对宫颈癌中HPV的自然病史进行了全面研究。在感染生殖道的40多种HPV类型中,已经定义了高危型HPV型以及可能或可能发生的高危型宫颈癌。2定期检查可以预防宫颈癌。
更新日期:2018-01-26
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