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Charged probes: turn-on selective fluorescence for RNA
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2017-11-09 00:00:00 , DOI: 10.1039/c7ob02423a
Bahareh Shirinfar 1, 2, 3, 4 , Humaira Seema 5, 6, 7 , Nisar Ahmed 1, 4, 8, 9
Affiliation  

RNA controls many biological processes. The selective detection and imaging of RNA molecules can provide information about their location, kinetics, and functions at the cellular level. The imidazolium-based positively charged probes would play a significant role in the deep investigation of RNA biomolecules to check their therapeutic potential and aid in the future rational molecular and drug design.

中文翻译:

带电探针:开启RNA的选择性荧光

RNA控制许多生物过程。RNA分子的选择性检测和成像可以提供有关其在细胞水平上的位置,动力学和功能的信息。基于咪唑鎓的带正电荷的探针将在RNA生物分子的深入研究中发挥重要作用,以检查其治疗潜力并有助于未来的合理分子和药物设计。
更新日期:2017-11-16
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