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N,N-dimethyl-d-glucosamine as an efficient ligand for copper-catalyzed Ullmann-type coupling of N-H heterocycles with aryl halides
Tetrahedron ( IF 2.1 ) Pub Date : 2017-11-14 , DOI: 10.1016/j.tet.2017.11.027
Jiao Jiao Wei , Wei Bin Song , Ye Fu Zhu , Bo Le Wei , Li Jiang Xuan

A new N,N-dimethyl-d-glucosamine ligand has been developed for the copper-catalyzed Ullmann-type coupling of N-H heterocycles (e.g., indoles, benzimidazoles, pyrazoles and triazoles) with aryl halides. This method was accomplished not only featuring excellent yields, mild reaction conditions and simple operation, but also showing eco-friendly and broad-spectrum substrates, and could be widely used in the construction of N-aryl heterocyclic systems.



中文翻译:

ÑÑ二甲基d葡糖胺作为一种有效的配体的铜催化的Ullmann型偶合Ñ -H杂环与芳基卤

一个新的ÑÑ二甲基d -葡糖胺的配体已用于铜催化的Ullmann型偶合开发Ñ -H杂环(例如,吲哚,苯并咪唑,吡唑和三唑)与芳基卤化物。该方法不仅收率高,反应条件温和,操作简单,而且具有环保和广谱底物的特点,可广泛用于N-芳基杂环体系的构建。

更新日期:2017-11-14
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