The trifluoromethylthio group is of rising interest in medicinal, agrochemical, and materials chemistry. Although several strategies for the introduction of this functional group have been described, new synthetic methods are needed. A novel ionic liquid, 1-n-butyl-3-methylimidazolium trifluoromethylthiolate, has been developed and is herein reported as an efficient and recyclable in situ generated trifluoromethylthiolating reagent for alkyl halides, sulfonates, and even unactivated alcohols under solvent-free conditions.

中文翻译：

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用于烷基卤和醇的快速和无溶剂亲核三氟甲硫基化的离子液体

三氟甲硫基在医药、农用化学品和材料化学中越来越受到关注。尽管已经描述了引入该官能团的几种策略，但仍需要新的合成方法。一种新型离子液体 1-n-丁基-3-甲基咪唑鎓三氟甲基硫醇盐已被开发并在本文中被报道为一种有效且可回收的原位三氟甲基硫醇化试剂，用于在无溶剂条件下用于烷基卤化物、磺酸盐甚至未活化的醇。