DEAD-Promoted Oxidative Ugi-Type Reaction Including an Unprecedented Ugi Amidation Assisted by Dicarboxylic Acids,European Journal of Organic Chemistry

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DEAD-Promoted Oxidative Ugi-Type Reaction Including an Unprecedented Ugi Amidation Assisted by Dicarboxylic Acids
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-11-15 06:45:44 , DOI: 10.1002/ejoc.201701323
Jiankun Wang ₁ , Yilin Sun ₁ , Guangji Wang ₁ , Le Zhen ₁

Affiliation

A new oxidative Ugi-type reaction promoted by DEAD (diethyl azodicarboxylate) leads to α-amino imides or amides when mono- or dicarboxylic acids, respectively, are used. This metal-free transformation is highly efficient and has a good tolerance of various functional groups.

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