Herein, we report a highly regioselective gold-catalyzed formal hydration of propargylic gem-difluorides. Not only does this transformation provide access to versatile fluorinated building blocks that were difficult or hardly possible to access beforehand, but it also represents a rare case of a highly regioselective gold-catalyzed hydroalkoxylation of internal alkynes and puts forward the utility of the difluoromethylene unit as a directing group in catalysis.

中文翻译：

---

炔丙基宝石-二氟化物的高区域选择性金催化形式水合†

在本文中，我们报道了炔丙基宝石-二氟化物的高度区域选择性金催化的正式水合。这种转化不仅提供了难以或几乎不可能预先获得的多用途氟化结构单元的途径，而且还代表了内部炔烃具有高度区域选择性的金催化加氢烷氧基化的罕见情况，并提出了二氟亚甲基单元的实用性。催化中的指导基团。