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Does CSF1R Blockade Turn into Friendly Fire?
Cancer Cell ( IF 48.8 ) Pub Date : 2017-Nov-13 , DOI: 10.1016/j.ccell.2017.10.012
Tim F Greten 1
Affiliation  

In this issue of Cancer Cell, Kumar et al. describe how CSF1R blockade induces not only an expected deprivation of tumor-associated macrophages, but also an accumulation of tumor-infiltrating polymorphonuclear mononuclear cells caused by Cxcl-1 released from cancer-associated fibroblasts.

中文翻译:


CSF1R 封锁会变成误伤吗?



在本期《癌细胞》中,Kumar 等人。描述了 CSF1R 阻断如何不仅诱导肿瘤相关巨噬细胞的预期缺失,而且还诱导由癌症相关成纤维细胞释放的 Cxcl-1 引起的肿瘤浸润多形核单核细胞的积累。
更新日期:2017-11-13
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