A palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters have been developed. This cyclization reaction shows excellent regioselectivity and good functional group tolerance to obtain five-membered nitrogenated heterocyclic conjugated trienes in moderate to excellent yields. The resulting conjugated trienes could be facilely converted to highly substituted benzenes through Diels-Alder reactions.

中文翻译：

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钯催化的1,6-烯炔乙酸酯的环异构化反应形成五元氮化杂环共轭三烯

已经开发了钯催化的1，6-烯炔乙酸酯的环异构化反应。该环化反应显示出优异的区域选择性和良好的官能团耐受性，以中等至优异的产率获得了五元氮化杂环共轭三烯。所得的共轭三烯可通过狄尔斯-阿尔德反应容易地转化为高度取代的苯。