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Palladium-Catalyzed Ring-Opening Coupling of Cyclobutenols with Aryl Halides
Synlett ( IF 1.7 ) Pub Date : 2017-10-20 , DOI: 10.1055/s-0036-1589117
Takanori Matsuda , Takeshi Matsumoto , Akira Murakami

A palladium(0)-catalyzed ring-opening cross-coupling reaction between tert -cyclobutenols and aryl halides produces γ-arylated β,γ-unsaturated ketones. In the case of aryl halides bearing functional groups at the ortho position, the resulting ring-opened ketones undergo intramolecular condensation to afford bicyclic aromatic compounds.

中文翻译:

钯催化环丁烯醇与芳基卤的开环偶联

钯(0)催化的叔环丁烯醇和芳基卤化物之间的开环交叉偶联反应产生γ-芳基化的β,γ-不饱和酮。在邻位带有官能团的芳基卤化物的情况下,所得开环酮进行分子内缩合以提供双环芳族化合物。
更新日期:2017-10-20
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