Herein we report the first synthesis of protected boronocysteine. The target compound was prepared via copper-catalysed diastereoselective nucleophilic borylation of a sulfinimine. After deprotection to give the amine as the hydrochloride salt, four boronocysteine amide derivatives were prepared through reaction with a variety of different active acylating agents.

中文翻译：

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硼代半胱氨酸的合成

在此，我们报告了受保护硼半胱氨酸的首次合成。目标化合物是通过亚磺亚胺的铜催化非对映选择性亲核硼酸化制备的。在脱保护得到胺盐酸盐后，通过与多种不同的活性酰化剂反应制备了四种硼代半胱氨酸酰胺衍生物。