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Efficient Method to Synthesize Benzhydrazides by In Situ Oxidation/Coupling of Benzylic Alcohols with Azodicarboxylates
Synlett ( IF 1.7 ) Pub Date : 2017-10-16 , DOI: 10.1055/s-0036-1591311
Kobra Azizi 1 , Akbar Heydari 1
Affiliation  

An efficient synthesis of benzhydrazides has been achieved through the direct acylation of azodicarboxylates with benzylic alcohols in moderate to high yields. The method represents the first practical approach to amides containing a hydrazine structural unit from benzylic alcohols.

中文翻译:

苯甲醇与偶氮二羧酸酯原位氧化/偶联合成苯酰肼的有效方法

通过偶氮二羧酸酯与苯甲醇的直接酰化,以中等至高产率实现了苯甲酰肼的有效合成。该方法代表了第一个实用的方法,用于从苯甲醇中制备含有肼结构单元的酰胺。
更新日期:2017-10-16
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