The convergent synthesis of two biologically significant classes of trisubstituted hexahydroimidazo[1,2-a]pyridine and 1,4-diazepane derivatives from readily available aromatic aldehydes, ketones, and ethane-1,2-diamine is reported. This protocol is promoted by the highly effective l -phenylalanine triflate catalyst through intermolecular annulation, and tolerates a variety of functional groups with excellent yields.

中文翻译：

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l-苯丙氨酸三氟甲磺酸盐作为有机催化剂用于三取代六氢咪唑并[1,2-a]吡啶和1,4-二氮杂环衍生物的不同方法

据报道，从易于获得的芳香醛、酮和乙烷-1,2-二胺中聚合合成两种具有生物学意义的三取代六氢咪唑并 [1,2-a] 吡啶和 1,4-二氮杂环衍生物。该方案由高效的 l-苯丙氨酸三氟甲磺酸酯催化剂通过分子间环化促进，并以优异的产率耐受各种官能团。