当前位置: X-MOL 学术Synlett › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Radical Allylation: E-Selective Radical Conjugate Addition–Elimination Reaction from Morita–Baylis–Hillman Adducts
Synlett ( IF 2 ) Pub Date : 2017-09-27 , DOI: 10.1055/s-0036-1590922
Thierry Lequeux , Cyril Lebargy , Coralie De Schutter , Remi Legay , Emmanuel Pfund

Triethylborane-mediated radical allylation was performed from Morita–Baylis–Hillman alcohols with no need of protecting group. The radical conjugated addition–elimination reaction is highly selective, and trisubstituted E-alkenes were obtained. This reaction opened a new route for the preparation of functionalized α,β-unsaturated ketones.

中文翻译:

自由基烯丙基化:来自 Morita-Baylis-Hillman 加合物的 E 选择性自由基共轭加成消除反应

三乙基硼烷介导的自由基烯丙基化是由 Morita-Baylis-Hillman 醇进行的,不需要保护基团。自由基共轭加成消除反应具有高度选择性,得到了三取代的 E-烯烃。该反应为功能化α,β-不饱和酮的制备开辟了一条新途径。
更新日期:2017-09-27
down
wechat
bug