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Breaking the Barrier: Host Cell Invasion by Lujo Virus
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2017-11-08 , DOI: 10.1016/j.chom.2017.10.014 Stefan Kunz , Juan Carlos de la Torre
中文翻译:
打破障碍:Lujo病毒入侵宿主细胞
更新日期:2017-11-08
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2017-11-08 , DOI: 10.1016/j.chom.2017.10.014 Stefan Kunz , Juan Carlos de la Torre
Lujo virus (LUJV) is an arenavirus that emerged in 2008 associated with a cluster of human cases of severe hemorrhagic fever. In this issue of Cell Host & Microbe, Raaben et al. (2017) identify neuropilin (NRP)-2 as cell surface receptor and the tetraspannin protein CD63 as intracellular entry factor for LUJV.
中文翻译:
打破障碍:Lujo病毒入侵宿主细胞
Lujo病毒(LUJV)是一种2008年出现的舞台病毒,与一系列严重的出血热人类病例相关。在本期《细胞宿主与微生物》中,Raaben等人。(2017)确定神经pil蛋白(NRP)-2为细胞表面受体,四环精蛋白CD63为LUJV的细胞内进入因子。