The prevalence of allergic diseases has increased in the past few decades. Bio-aerosol proteins and their chemical modifications, such as 3-nitrotyrosine (3-NT), in the atmosphere have been attracting attention due to their promotive effects on allergies. 3-NT is generated from the amino acid, tyrosine, through a reaction with ozone (O₃) and nitrogen dioxide (NO₂). However, the underlying mechanisms have not yet been elucidated in detail. Therefore, we measured 3-NT and evaluated the relationships among 3-NT and various pollutants such as sulfur dioxide (SO₂), NOx (NO + NO₂), ozone (O₃), PM₇, total suspended particulate matter (TSP) containing proteins, humidity, and temperature. 3-NT positively correlated with O₃, SO₂, humidity, and temperature, and negatively correlated with NOx. A multiple regression analysis showed that 3-NT positively associated with O₃, humidity, and PM₇. O₃ positively associated with 3-NT and PM₇, and negatively associated with NOx and humidity. These results suggest that 3-NT is generated from PM proteins through a reaction with O₃ under high humidity conditions, and that the measurement of 3-NT is important and useful for the research of O₃.

在过去的几十年中，过敏性疾病的流行有所增加。大气中的生物气溶胶蛋白及其化学修饰物（例如3-硝基酪氨酸（3-NT））因其对过敏的促进作用而受到关注。通过与臭氧（O ₃）和二氧化氮（NO ₂）的反应，由氨基酸酪氨酸生成3-NT 。但是，尚未详细阐明其基本机制。因此，我们测量了3-NT并评估了3-NT与各种污染物之间的关系，例如二氧化硫（SO ₂），NOx（NO + NO ₂），臭氧（O ₃），PM ₇，即包含蛋白质，湿度和温度的总悬浮颗粒物（TSP）。3-NT与O ₃，SO ₂，湿度和温度呈正相关，与NOx呈负相关。多元回归分析表明3-NT与O ₃，湿度和PM ₇正相关。O ₃与3-NT和PM ₇正相关，与NOx和湿度负相关。这些结果表明3-NT是在高湿度条件下通过与O ₃反应从PM蛋白产生的，并且3-NT的测定对于O ₃的研究是重要的和有用的。