Prediabetes (or intermediate hyperglycaemia) is defined as a state in which glycaemic variables are higher than normal, lower than the threshold for diabetes, but have reached a level shown to pose an increased risk of developing diabetes in the future.¹ In 2012, Tabák and colleagues¹ argued that the definition of prediabetes should no longer be glucocentric. Prediabetes is associated with generalised microvascular dysfunction and evidence has increasingly shown that patients with prediabetes have microvascular sequelae representing end-organ damage typical of diabetes.

中文翻译：

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糖尿病前期：摆脱糖原性定义

糖尿病前期（或中度高血糖）被定义为一种状态，其中血糖变量高于正常水平，低于糖尿病阈值，但已达到显示将来增加患糖尿病风险的水平。¹ 2012年，Tabak及其同事¹认为，糖尿病前期的定义不应再以葡萄糖为中心。前驱糖尿病与广泛的微血管功能障碍有关，越来越多的证据表明，前驱糖尿病患者具有微血管后遗症，代表了典型的糖尿病终末器官损害。